Science

Science & Validation

Sweat
Biosensing

Every workout is a physiological challenge.

Wearables provide movement and cardiovascular context. Sweat biosensing adds biochemical measurement.

GYM3000.com is developing biosensing infrastructure for biochemical measurement in sweat.

TimePurchase is its biosensing division.

Biosensors and measurement science for biochemical signals in sweat and the longitudinal study of physiological response, recovery and resilience.

IMeasurement

Biochemistry in real-world exercise.

Maintaining measurement validity from sample to interpretation.

  1. Sample
  2. Measure
  3. Interpret

IISignals

Selected by evidence.

Biochemical signals

Metabolites · Ions · Acid–base chemistry

Context

Physical conditions of measurement

Analytical performanceStabilityIntegrationPhysiological relevance

Evidence determines the final combination.

IIITime

One measurement shows a moment. Repeated measurements show change.

Exercise under comparable conditions provides a repeatable physiological challenge.

Response

What changes with the challenge?

Recovery

How does the response evolve after the challenge?

Resilience

How do response and recovery patterns change over time under comparable conditions?

Figure 1 — Conceptual framework for response, recovery and resilience.

IVEvidence

From measurement to evidence.

Biological information requires a validated measurement chain.

  1. 01SampleWas a valid sample collected?
  2. 02SignalWas the measurement stable and reproducible?
  3. 03AnalyteDid the result agree with an appropriate reference method?
  4. 04Human responseWas the response pattern reproducible under comparable conditions?
  5. 05UseDid it add useful information for a defined purpose?

Evidence determines how far each claim can advance.

VTranslation

GYM3000.com

Biosensing Infrastructure

FitButlr™

Distribution & Interfaces

TimePurchase™

Biosensing Division